Skip the introduction by the Edge editor, and go straight to Dennett's rejoinder; a choice excerpt:
Pomposity can be amusing, but pomposity sitting like an oversized hat on top of fear is hilarious. Wieseltier is afraid that the humanities are being overrun by thinkers from outside, who dare to tackle their precious problems--or "problematics" to use the, um, technical term favored by many in the humanities. He is right to be afraid. It is true that there is a crowd of often overconfident scientists impatiently addressing the big questions with scant appreciation of the subtleties unearthed by philosophers and others in the humanities, but the way to deal constructively with this awkward influx is to join forces and educate them, not declare them out of bounds.
All this brings to mind an earlier encounter with the old fraud.
(Thanks to Nathan Jun for the pointer to Dennett's piece.)